山根 順子　博士（医学）
Junko Yamane, Ph.D.

Current Job:
Postdoctoral Researcher
Center for iPS Research and Application (CiRA)
Kyoto University
53 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto 606-8507, JAPAN
Email: yamane-j (a) cira.kyoto-u.ac.jp

Education and Job Career
2012.4- Researcher, Center for iPS Research and Application, Kyoto University
2010.4-2012.3 Post-doctoral fellow, Center for Disease Biology and Integrative Medicine, Graduate School and Faculty of Medicine, The University of Tokyo
2009.4-2010.3 Post-doctoral fellow, Health Research Institute, AIST
2008.1-2009.3 Post-doctoral fellow, Hyogo College of Medicine
2007.6-2007.12 Technical staff, Hyogo College of Medicine
2006.4-2007.3 Researcher, Kyoto Prefectural University of Medicine
2007.11 Ph.D. Medicine, Kyoto University
2002.3 M.S. Biology, Kobe University
2000.3 B.S. Biology, Kobe University

Publications
【Reviewed Publications】*...Corresponding

1. Down regulation of matrix metalloproteinase-9 mRNA by valproic acid plays a role in inhibiting the shedding od MHC class I-related molecules A and B on the surface of human osteosarcoma cells, Yamanegi, K*., Yamane, J*., Kobayashi, K., Ohyama, H., Nakasho, K., Yamada, N., Hata, M., Fukunaga, S., Futani, H., Okamura, H., and Terada, N., Oncol. Rep., 28(5): 1585-1590 (2012).
2. Valproic acid cooperates with hydralazine to augment the susceptibility of human osteosarcoma cells to Fas- and NK cell-mediated cell death, Yamanegi, K*., Yamane, J*., Kobayashi, K., Kato-Kogoe, M., Ohyama, H., Nakasho, K., Yamada, N., Hata, M., Fukunaga, S., Futani, H., Okamura, H., and Terada, N., Int. J. oncol., 41(1) : 83-91 (2012).
3. Effects of methylmercury exposure on neuronal differentiation of mouse and human embryonic stem cells, He, X., Imanishi, S., Sone, H., Nagano, R., Qin, XY., Yoshinaga, J., Akanuma, H., Yamane, J., Fujibuchi, W., and Ohsako, S., Toxicol. Lett., 212(1) : 1-10 (2012).
4. Prediction of Chemical Toxicity by Network-based SVM on ES-cell Validation System, Fujibuchi, W., Aburatani, S., Yamane, J., Imanishi, S., Akanuma, H., Sone, H., and Ohsako, S., The Proceedings of the 2011 Joint Conference of CBI-Society and JSBi, Kobe (2011).
5. Formation of microvilli and phosphorylation of ERM family proteins by CD43, a potent inhibitor for cell adhesion: cell detachment is a potential cue for ERM phosphorylation and organization of cell morphology, Yamane, J., Ohnishi, H., Sasaki, H., Narimatsu, H., Ohgushi, H. and Tachibana, K., Cell Adh. Migr. 5(2): 119-132 (2011).
6. Sodium valproate, a histone deacetylase inhibitor, augments the expression of cell-surface NKG2D ligand, MICA/B, without increasing its soluble form to enhance susceptibility of human osteosarcoma cells to NK cell-mediated cytotoxicity, Yamanegi, K*., Yamane , J*., Kobayashi, K., Kato-Kogoe, N., Ohyama, H., Nakasho, K., Yamada, N., Hata, M., Nishioka, T., Fukunaga, S., Futani, H., Okamura, H., and Terada, N., Oncol. Rep., 24(6): 1621-1627 (2010).
7. The involvement of IL-23 and the Th17 pathway in periodontitis,Ohyama, H., Kato-Kogoe, N., Kuhara, A., Nishimura, F., Nakasho, K., Yamanegi, K., Yamada, N., Hata, M., Yamane, J., and Terada, N., J. Dent. Res., 88(7): 633-638 (2009).
8. Sodium valproate, a histone deacetylase inhibitor, decreases the secretion of soluble Fas by human osteosarcoma cells and increases their sensitivity to Fas-mediated cell death,Yamanegi, K*., Yamane, J*., Hata, M., Ohyama, H., Yamada, N., Kato-Kogoe, N., Futani, H., Nakasho, K., Okamura, H., and Terada, N., J. Cancer Res. Clin. Oncol., Jul;135(7):879-89, (2009).
9. Chloride-dependent acceleration of cell cycle via modulation of Rb and cdc2 in osteoblastic cells, Maki, M., Miyazaki, H., Nakajima, K., Yamane, J., Niisato, N., Morihara, T., Kubo, T., and Marunaka, Y., Biochem. Biophys. Res. Commun., Oct 5;361(4):1038-43 (2007).
10. Functional involvement of TMF/ARA160 in Rab6-dependent retrograde membrane traffic, Yamane, J., Kubo, A., Nakayama, K., Yuba-Kubo, A., Katsuno, T., Tsukita, S., and Tsukita, S., Exp. Cell Res., Oct 1; 313(16): 3472-85 (2007).